Over its 150 years of operation, Mayo Clinic has contributed heartily to the practice of medicine, medical research and the education of future health care professionals. The most pervasive may be showcasing the integrated, multispecialty group practice called the Mayo Model of Care.

The most obvious may be the Nobel Prize for discovering cortisol.

But the most recent show Mayo Clinic’s response to the changing medical ecosystem. Improving devices, capitalizing on digital opportunities and addressing unmet patient needs have led to exciting contributions to health care. Here are just 10 brought to you in part by Mayo Clinic Ventures and business collaborators.

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